Protein kinetic signatures of the remodeling heart following isoproterenol stimulation

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Protein kinetic signatures of the remodeling heart following isoproterenol stimulation.

Protein temporal dynamics play a critical role in time-dimensional pathophysiological processes, including the gradual cardiac remodeling that occurs in early-stage heart failure. Methods for quantitative assessments of protein kinetics are lacking, and despite knowledge gained from single-protein studies, integrative views of the coordinated behavior of multiple proteins in cardiac remodeling ...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 2014

ISSN: 0021-9738

DOI: 10.1172/jci73787